Bersanelli silvia pinal biography

The Society for Immunotherapy of Cancer (SITC) will begin accepting submissions of regular abstracts and late-breaking abstract applications for the 36th.
PubMed Central.
Physical and social isolation during COVID-19 - How did it impact the functional status of people with advanced respiratory disease?

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Linker-free conjugation and specific cell targeting of antibody functionalized iron-oxide nanoparticles

PubMed Central

Xu, Yaolin; Baiu, Dana C.; Sherwood, Jennifer A.; McElreath, Meghan R.; Qin, Ying; Lackey, Kimberly H.; Otto, Mario; Bao, Yuping

2015-01-01

Specific targeting is a key step to realize the full potential of iron oxide nanoparticles in biomedical applications, especially tumor-associated diagnosis and therapy. Here, we developed anti-GD2 antibody conjugated iron oxide nanoparticles for highly efficient neuroblastoma cell targeting. The antibody conjugation was achieved through an easy, linker-free method based on catechol reactions. The targeting efficiency and specificity of the antibody-conjugated nanoparticles to GD2-positive neuroblastoma cells were confirmed by flow cytometry, fluorescence microscopy, Prussian blue staining and transmission electron microscopy. These detailed studies indicated that the receptor-recognition capability of the antibody was fully retained after conjugation and the conjugated nanoparticles quickly attached to GD2-positive cells

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Abstract Titles

1Poster PresentationDissecting β-catenin associated inflammation in patients with desmoid fibromatosis to identify prognostic biomarkersLaura Bergamaschi; Federica Perrone; Francesca Rini; Licia Rivoltini; Chiara Castelli, PhD; Alessandro Gronchi; Chiara Colombo; Viviana VallacchiBiomarkers, Immune Monitoring, and Novel TechnologiesImmune monitoring;Inflammation2Poster PresentationQuantitation of CD137 and Nectin-4 expression across multiple tumor types to support indication selection for BT7480, a Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™)Heather Cohen; Carly Campbell; Kristen Hurov; Johanna Lahdenranta; Tara Gelb; David Galbraith; Dan Rozelle; Mate L. Nagy; Qingyan Au; Erinn A. Parnell, PhD; Phil Brandish; Sebastien Hazard; Dominic Smethurst; Nicholas Keen; Stephen J. BlakemoreBiomarkers, Immune Monitoring, and Novel TechnologiesBiomarkers;Bispecifics;Costimulation;Gene expression;Immune contexture;Immune monitoring;Solid tumors;T cell;Targeted therapy;Tumor microenvironment3Poster PresentationDevelopment

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original articleJournalDateTitleAuthorsAll Authors2001[GO]Career Development and Transition for Exceptional Individuals2023―Jul―18Impact of COVID-19 on the Employment of Transition-Aged Military-Dependent or Connected Autistic YouthHolly Whittenburg, Jennifer McDonough, Carol Schall, Thomas Dubois, Vivian Vitullo, Paul Wehman2002[GO]Cell Transplantation2023―Jul―03Mechanisms of Potential Therapeutic Utilization of Mesenchymal Stem Cells in COVID-19 TreatmentYuyin Fang, Peizhen Lao, Longqian Tang, Jingyi Chen, Yuxi Chen, Lei Sun, et al. (+2)

Wenwen Tan, Xingliang Fan

2003[GO]Cell Transplantation2022―Apr―19Modified mRNA-Based Vaccines Against Coronavirus Disease 2019Aline Yen Ling Wang2004[GO]Cell Transplantation2021―Nov―10High Induction of IL-6 Secretion From hUCMSCs Optimize the Potential of hUCMSCs and TCZ as Therapy for COVID-19-Related ARDSHuei-Yu Lo, Shun-Ping Cheng, Jing-Long Huang, Kuo-Ting Chang, Yu-Lung Chang, Chien-Hsu